Kosin Medical Journal

The Natural Course of Total Kidney Volume in Patients with Autosomal Dominant Polycystic Kidney Disease undergoing Hemodialysis: Ye Na Kim, Yeonsoon Jung, Ho Sik Shin, Hark Rim, Jung Gu Park, Dong Yeol Lee, Joong Kyung Kim; Kosin Med J. 2021;36(2):109-115. Published online December 31, 2021; DOI: https://doi.org/10.7180/kmj.2021.36.2.109

Abstract PDF PubReader ePub: Objectives
The natural course of native kidneys after hemodialysis initiation in patients with autosomal dominant polycystic kidney disease (ADPKD) remains poorly understood.
Methods
We measured the total volumes of native kidneys in 12 patients who had at least one enhanced computed tomography (CT) image both before and after initiation of hemodialysis (group 1) and in 18 patients who had no image before dialysis but more than two images after dialysis (group 2). In patients with images, the last image was used for analysis only after dialysis.
Results
The mean total kidney volume (TKV) (± SD) before hemodialysis initiation was 3132 ± 1413 mL and the mean TKV of the last image was 3047 ± 1323 mL in group 1. The mean TKV change rate (%) was −5.2 ± 27.4% (P > 0.05) during follow-up of 3.9 ± 1.9 years in group 1. The mean TKV change rate was 2.8 ± 34.4% (P > 0.05) in group 2. The follow-up period after dialysis initiation ranged from 4.2 ± 4.7 to 8.0 ± 5.2 years.
Conclusions
The results suggest that the TKV of native polycystic kidneys decreases substantially after hemodialysis initiation. This reduction occurs mainly during the early post-hemodialysis period and followed by a slow enlargement of TKV.

A Case of Lactate Containing Peritoneal Dialysis Solution Induced Lactic Acidosis Corrected by Changing to Hemodialysis: Eun Bin Kim, Ki Seung Kim, Su Mi Lee, Young Ki Son, Seong Eun Kim, Won Suk An; Kosin Med J. 2017;32(1):105-110. Published online June 30, 2017; DOI: https://doi.org/10.7180/kmj.2017.32.1.105

Abstract PDF PubReader ePub: Elevated lactate levels are associated with acute illnesses, and the mortality is high. Here, we report a case of lactate-containing peritoneal dialysis (PD) solution inducing lactic acidosis corrected by changing to hemodialysis (HD). This 70-year-old female patient was treated with PD 8 months previously for end-stage renal disease caused by diabetes mellitus. She was admitted complaining of general weakness. Initial lactate level was 22.1 mg/dL and increased to 62.4 mg/dL showing high anion gap metabolic acidosis and compensatory hyperventilation. There are no definite causes of lactic acidosis besides the use of PD solutions containing a lactate component. The patient's lactate level was decreased after temporarily changing the dialysis modality to HD. Her lactate level was increased again after restarting PD, and decreased to normal after restarting HD. We report this case because physicians should consider lactate-containing PD solution as a possible cause of lactic acidosis.

A Case of Severe Renal Osteodystrophy with Pathologic Fractures of Vertebra: Song Ju Lee, Eun Mi Lee, Hark Rim, Yeon Soon Jung, Jae Ho Jang; Kosin Med J. 2008;23(4):234-238. Published online December 31, 2008

The interdialytic weight gain as a nutritional parameter in hemodialysis patients: Ho Sik Shin, Yeon Soon Jung, Hark Rim; Kosin Med J. 2006;21(1):126-133.

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