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Case Report
A Case of Infective Endocarditis Occurred during Treatment for Infectious Spondylitis Accompanied by Peptostreptococcus Anaerobius Bacteremia
Byung Hee Lee, Myung Hee Lee, Sook Kyung Oh, Ji Young Seo, Joon Hoon Jeong, Jae Woo Lee
Kosin Medical Journal 2012;27(2):185-190.
DOI: https://doi.org/10.7180/kmj.2012.27.2.185
Published online: December 27, 2012

1Department of Internal Medicine, Wallace Memorial Baptist Hospital, Busan, Korea.

2Department of Cardiology, College of Medicine, Kosin University, Busan, Korea.

Corresponding Author: Joon Hoon Jeong, Department of Internal Medicine, Wallace Memorial Baptist Hospital, 374-75 Namsan-dong, Geumjeong-gu, Busan 609-728, Korea. TEL: +82-51-580-1202, FAX: +82-51-583-7114, jjhoon69@yahoo.co.kr
• Received: July 10, 2012   • Revised: September 14, 2012   • Accepted: October 17, 2012

Copyright © 2012 Kosin University College of Medicine

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  • It is necessary to distinguish between pyogenic and tuberculous spondylitis of infectious spondylitis, if it is pyogenic spondylitis, antimicrobial therapy should be directed against an identified microorganism and clinical assessment should be done at 4 weeks. But if microorganism is a anaerobic bacteria, especially Peptostreptococcus anaerobius, combination antibiotic therapy should be considered bacause it may be a component of mixed infections as a passenger and have abilities to induce abscesses, other bacterial growth as a synergy effect. In addition, echocardiography may be necessary because pyogenic spondylitis is associated with infective endocarditis about 12%. We report a 64-year-old man who was treated for infectious spondylitis accompanied by Peptostreptococcus anaerobius bacteremia, but had to undergo heart surgery because an attack of infective endocarditis with systemic embolism during hospitalization.
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Fig. 1
Spine MRI shows diffuse contrast enhancement of prevertebral soft tissue and endplate at L5-S1 (arrow).
kmj-27-185-g001-l.jpg
Fig. 2
Septic emboli identified according to imaging modalities (arrow). (A) Contrast-enhanced abdominal CT shows wedge shaped low attenuated lesion at spleen. (B) Aggravated state of spleen after 8 weeks. (C) Brain MRI shows acute ischemic infarct in both occipital lobe. (D) CT angiography of femoral artery shows focal segmental occlusion at distal portion of right popliteal artery.
kmj-27-185-g002-l.jpg
Fig. 3
Vegetation on the posterior leaflet of mitral valve (arrow). (A) Transthoracic echocardiographic finding. (B) Transesophageal echocardiographic finding after 4 weeks.
kmj-27-185-g003-l.jpg
Table 1
Laboratory findings, events and antibiotics administered during hospitalization
kmj-27-185-i001-l.jpg

WBC, white blood cell; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; H, isoniazid; R, rifampin; E, ethambutol; Z, pyrazinamide

Figure & Data

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    • Endocarditis due to Gram Positive Anaerobic Cocci: First report of Peptoniphilus indolicus endocarditis and literature review
      Julie Lourtet-Hascoet, Sébastien Hascoet, Jean-Louis Galinier, Benoît Fontenel, Benoît Monteil, Eric Bonnet
      Clinical Infection in Practice.2021; 11: 100073.     CrossRef

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      A Case of Infective Endocarditis Occurred during Treatment for Infectious Spondylitis Accompanied by Peptostreptococcus Anaerobius Bacteremia
      Kosin Med J. 2012;27(2):185-190.   Published online December 27, 2012
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