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Yeon Myeong Shin 3 Articles
Immediate Changes of Glucose Metabolism After Gastretomy for Early Gastric Cancer in Patients with Type 2 Diabetes
Ki Hyun Kim, Yoon Hong Kim, Kyung Won Seo, Ki Young Yoon, Yeon Myeong Shin, Young Sik Choi, Bu Kyung Kim
Kosin Med J. 2021;36(1):25-33.   Published online June 30, 2021
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Abstract PDFPubReader   ePub   

It is well known that type 2 diabetes (T2DM) is dramatically improved after bariatric surgery, although the mechanisms have not been clearly identified. The skill required for gastric surgery for gastric cancer is very similar to that needed in bariatric surgery. In this study, we evaluated the immediate improvement of T2DM after gastrectomy for gastric cancer.


A total of nine patients who were diagnosed with early gastric cancer (EGC) and already had T2DM underwent a 75 g oral glucose tolerance test (OGTT) before surgery and within two weeks after gastrectomy. Glucose, insulin, and c-peptide were measured before, and 30 and 60 minutes after ingesting 75 g of glucose. From these trials, we calculated the HOMA-IR, insulinogenic index, Matsuda index, and area under the curve (AUC).


The mean age of participants was 57.23 ± 11.08 years and eight of them were men. HOMA-IR (4.2 vs. 2.3, P = 0.012) levels were decreased after surgery. There were no significant differences of insulinogenic index, fasting blood sugar before and after surgery. The Matsuda index (3.3 vs. 8.3, P = 0.002) was significantly increased and AUC (512.9 vs. 388.7 mg-hr/dL, P > 0.001) upon 75 g OGTT was significantly decreased after surgery.


Insulin sensitivity was immediately improved after gastrectomy for early gastric cancer in patients with T2DM.


Citations to this article as recorded by  
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    Jiwon Kim, Hyunsoo Kim, Sungil Im, Youngin Park, Hae-Young Lee, Sookyung Kwon, Youngsik Choi, Linda Sohn, Chulho Oak
    Kosin Medical Journal.2023; 38(1): 21.     CrossRef
Pseudoaneurysm of Proximal Splenic Artery Following Total Gastrectomy : A Case Report
Kyung Won Seo, Yeon Myeong Shin
Kosin Med J. 2009;24(2):257-260.   Published online December 31, 2009
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Mutation and Methylation of p16 Gene in the Gastric Tissues of Advanced Gastric Cancer Patients
Hee Kyung Chang, Young Ok Kim, Un Hee Kong, Yeon Myeong Shin, Kyung Heon Choi
Kosin Med J. 2004;19(1):34-40.
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KMJ : Kosin Medical Journal