Systemic Review for The Effectiveness of Current Conservative Treatment in Necrotizing Pancreatitis

Article information

Kosin Med J. 2014;29(1):11-16

Publication date (electronic) : 2014 December 17

doi : https://doi.org/10.7180/kmj.2014.29.1.11

¹Department of Internal Medicine, Dong-eui Medical Center, Busan, Korea

²Department of Internal Medicine, College of Medicine, Pusan National University, Busan, Korea

Corresponding Author: Ungseok Yang, Department of Internal Medicine, Pusan National University, 179, Gudeok-ro, Seo-gu, Busan, Korea TEL: +82-51-865-0067 FAX: +82-51-865-8002 E-mail: usyang112@gmail.com

Received 2013 October 17; Revised 2013 December 12; Accepted 2013 December 27.

Abstract

The standard treatment of pancreatic necrosis has been surgical necrosectomy. There has been debate on whether early surgical intervention can reduced by infected pancreatic necrosis (IPN). Early emergency laparotomy and multiple organ failure remain associated with high mortality. However, reports have presented during the last 10 years of survival of severe acute pancreatitis with medical management. Large and multicenter study showed that about two thirds of patients with necrotizing pancreatitis can be treated conservatively with relatively low mortality. Patients with IPN benefit from postponding intervention and minimal invasive treatment. We reviewed 4 literatures including 2 Korean institute reseached reports concerning non-surgical, conservative treatments of necrotizing pancreatitis including IPN. Large and multicenter study showed that about two thirds of patients with necrotizing pancreatitis can be treated conservatively with relatively low mortality.

Keywords: Acute pancreatitis; Infection; Necrosis; Treatment

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