Systemic Review for The Effectiveness of Current Conservative Treatment in Necrotizing Pancreatitis

Jungik Park; Ungseok Yang

doi:10.7180/kmj.2014.29.1.11

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Review Article Systemic Review for The Effectiveness of Current Conservative Treatment in Necrotizing Pancreatitis: Jungik Park¹, Ungseok Yang²; Kosin Medical Journal 2014;29(1):11-16.
DOI: https://doi.org/10.7180/kmj.2014.29.1.11
Published online: December 17, 2014

¹Department of Internal Medicine, Dong-eui Medical Center, Busan, Korea

²Department of Internal Medicine, College of Medicine, Pusan National University, Busan, Korea

Corresponding Author: Ungseok Yang, Department of Internal Medicine, Pusan National University, 179, Gudeok-ro, Seo-gu, Busan, Korea TEL: +82-51-865-0067 FAX: +82-51-865-8002 E-mail: usyang112@gmail.com

• Received: October 17, 2013 • Revised: December 12, 2013 • Accepted: December 27, 2013

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Abstract
References

Abstract

The standard treatment of pancreatic necrosis has been surgical necrosectomy. There has been debate on whether early surgical intervention can reduced by infected pancreatic necrosis (IPN). Early emergency laparotomy and multiple organ failure remain associated with high mortality. However, reports have presented during the last 10 years of survival of severe acute pancreatitis with medical management. Large and multicenter study showed that about two thirds of patients with necrotizing pancreatitis can be treated conservatively with relatively low mortality. Patients with IPN benefit from postponding intervention and minimal invasive treatment. We reviewed 4 literatures including 2 Korean institute reseached reports concerning non-surgical, conservative treatments of necrotizing pancreatitis including IPN. Large and multicenter study showed that about two thirds of patients with necrotizing pancreatitis can be treated conservatively with relatively low mortality.
Keywords: Acute pancreatitis; Infection; Necrosis; Treatment

References

1. Mouli VP, Sreenivas V, Garg PK. Efficacy of Conservative Treatment, Without Necrosectomy, for Infected Pancreatic Necrosis: A Systemic Review and Metaanalysis. Gastroenterology 2013;144:333–40.Article PubMed
2. Van Santvoort HC, Bakker OJ, Bollen TL, Besselink MG, Ahmed Ali U, Schrijver AM, et al. A Conservative and Minimally Invasive Approach to Necrotizing Pancreatitis Improves Outcome. Gastroenterology 2011;141:1254–63.Article PubMed
3. Lee JK, Kwak KK, Park JK, Yoon WJ, Lee SH, Ryu JK, et al. The efficacy of nonsurgical treatment of infected pancreatic necrosis. Pancreas 2007;34:399–404.Article PubMed
4. Song JH, Seo DW, Byun SW, Koo DH, Bae JH, Lee SS, et al. Outcome of intensive medical treatment in patients with infected severe necrotizing pancreatitis. Korean J Gastroenterol 2006;48:337–43.PubMed
5. Werner J, Feuerbach S, Uhl W, Buchler MW. Management of acute pancreatitis: from surgery to interventional intensive care. Gut 2005;54:426–36.Article PubMed PMC
6. Beger HG, Rau B, Mayer J, Pralle U. Natural course of acute pancreatitis. World J Surg 1997;21:130–5.Article PubMed
7. Bradley EL 3rd. A clinically based classification system for acute pancreatitis. Summary of the International Symposium on Acute Pancreatitis, Atlanta, Ga, September 11 through 13, 1992. Arch Surg 1993;128:586–90.Article PubMed
8. Garg PK, Madan K, Pande GK, Khanna S, Sathyanarayan G, Bohidar NP, et al. Association of extent and infection of pancreatic necrosis with organ failure and death in acute necrotizing pancreatitis. Clin Gastroenterol Hepatol 2005;3:159–66.Article PubMed
9. Isenmann R, Rau B, Beger HG. Bacterial infection and extent of necrosis are determinants of organ failure in patients with acucte necrotizing pancreatitis. Br J Surg 1999;86:1020–4.PubMed
10. Nathens AB, Curtis JR, Beale RJ, Cook DJ, Moreno RP, Romand JA, et al. Management of the critically ill patient with severe acute pancreatitis. Crit Care Med 2004;32:2524–36.Article PubMed
11. Johnson CD, Abu-Hilal M. Persistent organ failure during the first week as a marker of fatal outcome in acute pancreatitis. Gut 2004;531340–4.Article
12. Blum T, Maisonneuve P, Lowenfels AB, Lankisch PG. Fatal outcome in acute pancreatitis: Its occurrence and early prediction. pancreatology 2001;1:237–41.Article PubMed
13. Besselink MG, van Santvoort HC, Boermeester MA, Nieuwenhuijs VB, van Goor H, Dejong CH, et al. Timing and impact of infections in acute pancreatitis. Br J Surg 2009;96:267–73.Article PubMed
14. Banks PA, Freeman ML. Practice Parameters Committee of the American College of Gastroenterology. Practice guidelines in acute pancreatitis. Am J Gastrenterol 2006;101:2379–400.
15. Gurusamy KS, Farouk M, Tweedie JH. UK guidelines for the managemnt of acute pancreatitis: is it time to change? Gut 2005;54:1344–5.Article PubMed PMC
16. Wemer J, Feuerbach S, Uhl W, Büchler MW. Management of acute pancreatitis: from surgery to interventional intensive care. Gut 2005;54:426–36.Article PubMed PMC
17. Uhl W, Warshaw A, Imrie C, Bassi C, McKay CJ, Lankisch PG, et al. IAP guidelines for surgical management of acute pancreatitis. Pancreatology 2002;2:565–73.Article PubMed
18. Forsmark CE, Baillie J. AGA Institute Clinical Practice and Economics Committee; AGA Institute Governing Board. AGA institute technical review on acute pancreatitis. Gastroenterology 2007;132:2022–44.Article PubMed
19. Büchler MW, Gloor B, Müller CA, Friess H, Seiler CA, Uhl W. Acute necrotizing pancreatitis: treatment strategy according to the status of infection. Ann Surg 2000;232:619–26.Article PubMed PMC
20. Mier J, León EL, Castillo A, Robledo F, Blanco R. Early versus late necrosectomy in severe necrotizing pancreatitis. Am J Surg 1997;173:71–5.Article PubMed
21. Fernández-del Castillo C, Rattner DW, Makary MA, Mostafavi A, McGrath D, Warshaw AL. Debridement and closed packing for the treatment of necrotizing pancreatitis. Ann Surg 1998;228:676–84.PubMed PMC
22. Besseolink MG, Verwer TJ, Schoenmaeckers EJ, Buskens E, Ridwan BU, Visser MR, et al. Timing of surgical intervention in necrotizing pancreatitis. Arch Surg 2007;142:1194–201.Article PubMed
23. Balthazar EJ, Robinson DL, Megibow AJ, Ranson JH. Acute pancreatitis; value of CT in establishing prognosis. Radiology 1990;174:331–6.Article PubMed
24. Ranson JH, Rifkind KM, Roses DF, Fink SD, Eng K, Spencer FC. Prognostic signs and role of operative management in acute pancreatitis. Surg Gynecol Obstet 1974;139:69–81.PubMed
25. United Kingdom guidelines for the management of acute pancreatitis. British Society of Gastroenterology. Gut 1998;42:S1–13.PubMed PMC
26. Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. 1992. Chest 1992;101:1644–55.Article PubMed
27. Lee JK, Kwak KK, Park JK, Yoon WJ, Lee SH, Ryu JK, et al. The efficacy of nonsurgical treatment of infected pancreatic necrosis. Pancreas 2007;34:399–404.Article PubMed
28. Song JH, Seo DW, Byun SW, Koo DH, Bae JH, Lee SS, et al. Outcome of intensive medical treatments in patients with infected severe necrotizing pancreatitis. Korean J Gastroenterol 2006;48:337–43.PubMed
29. Van Santvoort HC, Besselink MG, Bakker OJ, Hofker HS, Boermeester MA, Dejong CH, et al. A step up approach or open necrosectomy for necrotizing pancreatitis. N Engl J Med 2010;362:1491–502.Article PubMed

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Systemic Review for The Effectiveness of Current Conservative Treatment in Necrotizing Pancreatitis

Kosin Med J. 2014;29(1):11-16. Published online December 17, 2014

DOI: https://doi.org/10.7180/kmj.2014.29.1.11

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