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HOME > Kosin Med J > Volume 30(2); 2015 > Article
Case Report
Meningoencephalitis associated with Parvovirus B19 Infection in an Immunocompetent Patient
Dae-Seung Lee, Jin-Hyung Lee, So-Young Huh, Min Jeong Kim, Meyung-Kug Kim, Bong-Goo Yoo
Kosin Medical Journal 2015;30(2):181-185.
DOI: https://doi.org/10.7180/kmj.2015.30.2.181
Published online: January 20, 2015

Department of Neurology, College of Medicine, Kosin University, Busan, Korea

Corresponding Author: Bong-Goo Yoo, MD, PhD Department of Neurology, Kosin University College of Medicine, 262 Gamcheon-ro, Seo-gu, Busan 49267, Korea TEL: +82-51-990-6364 FAX: +82-51-990-3077 E-mail: ybgne@kosinmed.or.kr
• Received: November 30, 2015   • Accepted: November 30, 2015

Copyright © 2015 Kosin University School of Medicine Proceedings

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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  • Parvovirus B19 (PVB19) infection is a rare cause of meningoencephalitis. A 53-year-old previously healthy woman presented with fever, headache, and multiple erythema on the both legs. Cerebrospinal fluid study revealed pleocytosis and elevated opening pressure and protein level. Brain MRI showed multiple, asymmetric, hyperintensity in the brain stem, basal ganglia, white matter, and gray matter. Anti-B19 IgM antibody and PCR for PVB19 were positive in serum. Clinician should consider PVB19 infection in any case of acute febrile illness with erythema and meningoencephalitis
  • Keywords: Meningoencephalitis; MRI; Parvovirus B19
Fig. 1.
Axial FLAIR images show multiple, diffuse, asymmetric hyperintensities involving pons, midbrain, temporal lobe, bilateral thalami, basal ganglia, deep white matter, and temporal and occipital cortex.
kmj-30-181f1.jpg
Fig. 2.
Follow-up FLAIR images 6 months later demonstrate normal without any residual lesions.
kmj-30-181f2.jpg
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    • Clinical manifestations and treatment outcomes of parvovirus B19 encephalitis in immunocompetent adults
      Jin-Sun Jun, Jangsup Moon, Jung-Ick Byun, Jun-Sang Sunwoo, Jung-Ah Lim, Soon-Tae Lee, Keun-Hwa Jung, Kyung-Il Park, Ki-Young Jung, Manho Kim, Sang Kun Lee, Kon Chu
      Journal of NeuroVirology.2017; 23(6): 903.     CrossRef

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      Meningoencephalitis associated with Parvovirus B19 Infection in an Immunocompetent Patient
      Kosin Med J. 2015;30(2):181-185.   Published online January 20, 2015
      DOI: https://doi.org/10.7180/kmj.2015.30.2.181
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