Skip Navigation
Skip to contents

KMJ : Kosin Medical Journal

OPEN ACCESS
SEARCH
Search

Articles

Page Path
HOME > Kosin Med J > Volume 28(1); 2013 > Article
Case Report
Two Cases of Increased Parasympathetic Nerve System in Irritable Bowel Syndrome with Diarrhea as a Predominant Symptom
Eui Kyu Kang, Jong Soon Choi
Kosin Medical Journal 2013;28(1):49-54.
DOI: https://doi.org/10.7180/kmj.2013.28.1.49
Published online: January 19, 2013
  • 298 Views
  • 2 Download

Department of Family Medicine, College of Medicine, Kosin University, Busan, Korea

Corresponding author: Jong Soon Choi, Department of Family Medicine, College of Medicine, Kosin University, #34, Amnamdong, Suhgu, Busan 602-030, Korea Tel: +82-51-990-6476, E-mail: fmcjs@naver.com
• Received: July 25, 2012   • Accepted: September 28, 2012

Copyright © 2013 Kosin University School of Medicine Proceedings

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

  • The irritable bowel syndrome(IBS) is a chronic functional gastrointestinal disorder, characterized by abdominal pain, bloating and bowel disturbance. The pathophysiology of IBS is very complicated. Recent studies indicate that the most important mechanisms include visceral hypersensitivity, abnormal gut motility, autonomic nervous system(ANS) dysfunction and disorder of regulation of the brain-gut axis. Patients with IBS frequently present impaired autonomic regulation. Heart rate variability(HRV) is an acknowledged tool for estimating autonomic function. We experienced two cases of increased parasympathetic nervous system by HRV in irritable bowel syndrome with diarrhea as a predominant symptom
Fig. 1.
Five-minute time & frequency domain indices of heart rate variability (case 1)
kmj-28-49f1.jpg
Fig. 2.
Five-minute time & frequency domain indices of heart rate variability (case 2)
kmj-28-49f2.jpg
  • 1.Aggarwal A, Cutts TF, Abell TL, Cardoso S, Familoni B, Bremer J, et al. Predominant symptoms in irritable bowel syndrome correlate with specific autonomic nervous system abnormalities. Gastroenterology 1994;106:945–50.ArticlePubMed
  • 2.Luczak H, Laurig W. An analysis of heart rate variability. Ergonomics 1973;16:85–97.ArticlePubMed
  • 3.Liu J, Hou X. A review of the irritable bowel syndrome investigation on epidemiology, pathogenesis and pathophysiology in China. J Gastroenterol Hepatol 2011;26:88l–93.Article
  • 4.Barclay GR, Turnberg LA. Effect of psychological stress on salt and water transport in the human jejunum. Gastroenterology 1987;93:91–7.ArticlePubMed
  • 5.Taylor CT, Keely SJ. The autonomic nervous system and inflammatory bowel disease. Auton Neurosci 2007;133:104–14.ArticlePubMed
  • 6.Evans PR, Bak YT, Shuter B, Hoschl R, Kellow JE. Gastroparesis and small bowel dysmotility in irritable bowel syndrome. Dig Dis Sci 1997;42:2087–93.PubMed
  • 7.Arad M, Abboud S, Radai MM, Adunsky A. Heart rate variability parameters correlate with functional independence measures in ischemic stroke patients. J Electrocardiol 2002;35:243–6.ArticlePubMed
  • 8.Hon EH LS. Electronic evaluations of the fetal heart rate patterns preceding fetal death, further observations. Am J Obstet Gynecol 1963;87:814–26.PubMed
  • 9.Aronson D, Mittleman MA, Burger AJ. Measures of heart period variability as predictors of mortality in hospitalized patients with decompensated congestive heart failure. Am J Cardiol 2004;93:59–63.ArticlePubMed
  • 10.Vinik AI, Maser RE, Mitchell BD, Freeman R. Diabetic autonomic neuropathy. Diabetes Care 2003;26:1553–79.ArticlePubMed
  • 11.Jeong KS. The outline of HRV. J Korean Acad Fam Med 2004;25:S528–32.
  • 12.Heart rate variability: standards of measurement, physiological interpretation and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Circulation 1996;93:1043–65.PubMed

Figure & Data

References

    Citations

    Citations to this article as recorded by  

      Country-specific access statistics

      CountryReference
      Excel Download
      • PubReader PubReader
      • ePub LinkePub Link
      • Cited
        CITED
        export Copy
        Close
      • Download Citation
        Download Citation
        Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

        Format:
        • RIS — For EndNote, ProCite, RefWorks, and most other reference management software
        • BibTeX — For JabRef, BibDesk, and other BibTeX-specific software
        Include:
        • Citation for the content below
        Two Cases of Increased Parasympathetic Nerve System in Irritable Bowel Syndrome with Diarrhea as a Predominant Symptom
        Kosin Med J. 2013;28(1):49-54.   Published online January 19, 2013
        Close
      • XML DownloadXML Download
      Figure

      KMJ : Kosin Medical Journal