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12 "Spinal"
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Funded articles
Case reports
Development of severe junctional bradycardia after dexmedetomidine infusion in a polypharmacy patient: a case report and literature review
Soeun Jeon, Eunsoo Kim, Sun Hack Lee, Sung In Paek, Hyun-Su Ri, Dowon Lee
Kosin Med J. 2023;38(1):50-55.   Published online December 7, 2022
DOI: https://doi.org/10.7180/kmj.22.113
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Abstract PDFPubReader   ePub   
The authors report a case of newly manifested severe junctional bradycardia following dexmedetomidine administration during spinal anesthesia in a polypharmacy patient. A 77-year-old woman receiving multiple medications, including a beta-blocker and a calcium channel blocker, underwent right total knee arthroplasty. After spinal anesthesia, intravenous dexmedetomidine was initiated as a sedative; her heart rate decreased, followed by junctional bradycardia (heart rate, 37–41 beats/min). Dexmedetomidine was discontinued, and a dopamine infusion was initiated. Seven hours after surgery, junctional bradycardia persisted; a temporary transvenous pacemaker was inserted, and the beta-blocker and calcium channel blocker were discontinued. The patient was discharged on postoperative day 11 without any sequelae. Anesthesiologists should be aware of dexmedetomidine’s inhibitory effects on the cardiac conduction system, especially in geriatric patients taking medications with negative chronotropic effects and in combination with neuraxial anesthesia.
The Importance of Lamina Size Measurement and Proper Implants Selection before Laminoplasty : Two Case Reports
Dong Hwan Kim, Su Hun Lee, Dong Ha Kim, Kyoung Hyup Nam, In Ho Han, Byung Kwan Choi
Kosin Med J. 2021;36(2):169-174.   Published online December 31, 2021
DOI: https://doi.org/10.7180/kmj.2021.36.2.169
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Abstract PDFPubReader   ePub   

Open door laminoplasty using plates is a safe and effective procedure for multi-level cord compression. To achieve stable laminar arch, various types of plate have been developed and used. Now, we introduce two rare complications related to the laminar shelf of plate.

In the first case, we used the wider laminar shelf plate because the elevated lamina did not fit well into the usual laminar shelf. During follow-up, cord compression due to laminar shelf was observed.

And in the second case, the laminar shelf of plate did not fit into the elevated lamina, so we inserted it with a little bit of force. But the patient’s symptom was not improved. On CT image, the inner cortical bone of the lamina was fractured.

To prevent these complications, surgeons need to consider the thickness of the lamina and the size of the laminar shelf before surgery.

Lethal Cardiac Complications in a Long-Term Survivor of Spinal Muscular Atrophy Type 1
Min-Jung Cho
Kosin Med J. 2019;34(1):47-51.   Published online June 30, 2019
DOI: https://doi.org/10.7180/kmj.2019.34.1.47
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Spinal muscular atrophy (SMA) is a rare neuromuscular disease characterized by degeneration of the anterior horn cells of the spinal cord and motor nuclei in the lower brainstem, resulting in hypotonia, progressive proximal muscle weakness, paralysis, and progressive respiratory insufficiency. We report the case of a 6-year-old girl diagnosed with spinal muscular atrophy type 1 (Werdnig-Hoffman disease) who has been treated at home with non-invasive ventilation (assist-control mode with a back-up respiratory rate of 26 per minute). She presented with an atrioventricular block and atrial fibrillation, as well as paroxysmal fluctuation of blood pressure and heart rate indicating autonomic dysfunction. Although it is known that patients with spinal muscular atrophy type 1 do not generally demonstrate cardiac problems, it can be concluded based on findings in our case that long-term survivors with spinal muscular atrophy type 1 may develop cardiac rhythm disturbances. We therefore recommend that the possibility of cardiac complications and autonomic dysfunction should be borne in mind in the management of such patients.

Original article
The Synergistic Effect of Intrathecally Administered Dexmedetomidine and Ketorolac on Mechanical Allodynia in Rats with Spinal Nerve Ligation
Yong Kwan Cheong, Yeon Dong Kim, Ju Hwan Lee, Hyang Do Ham, Seung Won Choi, Seon Jeong Park
Kosin Med J. 2016;31(2):113-121.   Published online January 20, 2016
DOI: https://doi.org/10.7180/kmj.2016.31.2.113
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Abstract Objectives

This research was carried out to identify the synergistic effect of dexmedetomidine and ketorolac on neuropathic pain alleviation.

Methods

The anti-allodynic effect of intrathecal dexmedetomidine and ketorolac was investigated in rats after L5 spinal nerve ligation (SNL). Mechanical allodynia was assessed using Von Frey filaments. Every day for 3 consecutive days, beginning on the 10th day after SNL, behavioral tests were carried out at 1, 2, and 4 hr after drug injection.

Results

Significant increases in ipsilateral paw withdrawal thresholds (PWTs) were observed 1, 2, and 4 hr after drug injection in the groups of rats which received intrathecal injection of either dexmedetomidine (group D) or ketorolac (group K), compared to group S (P< 0.05). And group DK, which received simultaneous intrathecal injection of both dexmedetomidine and ketorolac, showed statistically significantly higher ipsilateral PWTs than groups D and K, which received only one of them (P< 0.05).

Conclusions

The results of this research demonstrated the anti-allodynic effect of dexmedetomidine and ketorolac on neuropathic pain induced by SNL in rats. They also suggest that synergistic analgesia can be induced by the simultaneous injection of dexmedetomidine and ketorolac, and that combination therapy is an effective approach to treating chronic neuropathic pain syndrome.

Case reports
A Case of Lead Migration Caused by Involuntary Movement in Implanted Spinal Cord Stimulation
Ju-Deok Kim, Jeong-Gil Lee, Sang-Su Kim, Hye-Young Shin
Kosin Med J. 2014;29(1):69-73.   Published online December 17, 2014
DOI: https://doi.org/10.7180/kmj.2014.29.1.69
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Abstract PDFPubReader   
Abstract

Spinal cord stimulation (SCS) is a reliable clinical option for treatment of refractory chronic pain. It is known to be effective method for treating sympathetic pain, failed back surgery syndrome, and complex regional pain syndrome etc. The devices and implantation techniques for SCS are already highly developed and continuously improving, but there are some complications that can not be corrected easily. Lead migration is the most common complication after SCS. It can cause failure of SCS that can make discomfort to patients. Here we describe our experience of lead migration in implanted SCS which was inserted to a patient with complex regional pain syndrome patient.

Clinical Findings Mismatched with Radioligic and Electrodiagnostic Study in Decompression Sickness: A case report and review
Young Joo Sim, Ho Joong Jeong, Ghi Chan Kim
Kosin Med J. 2010;25(2):192-196.   Published online December 31, 2010
  • 233 View
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Original articles
The effects of Music Threapy on Depression and Quality of Life for Central Nervous System Injured Patients
Sung Bok Choi, Ho Joong Jeong, Young Joo Sim
Kosin Med J. 2010;25(1):35-41.   Published online June 30, 2010
  • 279 View
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A Clinical Analysis of Spinal Injuries in Severe Trauma Patients
Ju Ho Jeong, Dae Yong Kim, Chang Min Park
Kosin Med J. 2009;24(2):36-41.   Published online December 31, 2009
  • 181 View
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Tsutsugamushi Disease with Meningitis: Clinical Features and Cerebrospinal Fluid Findings
Kwang Soo Kim, Min Jeong Kim
Kosin Med J. 2009;24(2):125-129.   Published online December 31, 2009
  • 175 View
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Chiropractic Manipulation Treatment in Cervicogenic Headache
Jae Ho Jang, Eun Seong Sagong
Kosin Med J. 2008;23(4):107-110.   Published online December 31, 2008
  • 170 View
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Incidence Change of Traumatic Spinal Cord Injury in Busan
Kyung Moon Kang, Ghi Chan Kim, Ho Joong Jeong
Kosin Med J. 2007;22(2):83-88.   Published online December 31, 2007
  • 287 View
  • 0 Download
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Case report
Neuralgic Amyotrophy with Paraspinal Muscles Involvement
Po Sung Jun, Sang Wook Jeong, Ghi Chan Kim, Ho Joong Jeong
The Journal of Kosin Medical College. 1998;13(1-2):151-157.
  • 249 View
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KMJ : Kosin Medical Journal