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Review articles
Generative artificial intelligence and large language models in competency-based medical education: applications, challenges, and future directions
In Hwa Jeong, Heeyoung Kim, Hyunyong Hwang
Kosin Med J. 2026;41(2):114-125.   Published online June 23, 2026
DOI: https://doi.org/10.7180/kmj.26.173
  • 1,230 View
  • 22 Download
Abstract PDFPubReader   ePub   
Competency-based medical education emphasizes formative assessment and longitudinal portfolio review; however, the resulting workload is increasingly difficult for faculty members to sustain. Generative artificial intelligence (GenAI) and large language models (LLMs), such as ChatGPT, Gemini, and Claude, offer opportunities to alleviate these burdens while enriching teaching and learning. This narrative review synthesizes peer-reviewed literature published between January 2023 and April 2026, retrieved from PubMed/MEDLINE, Scopus, Web of Science, Google Scholar, and Education Resources Information Center (ERIC), on the practical applications of GenAI and LLMs in medical education. Five core domains were identified: simulation of clinical reasoning, formative assessment and e-portfolio evaluation, support for self-directed learning, curriculum design, and communication skills training. Important challenges and ethical considerations are also discussed, including cognitive offloading and the potential erosion of critical thinking, hallucinations and threats to academic integrity, data privacy and institutional compliance concerns, and the risk of widening the digital divide. Future directions include multimodal LLMs and integrated clinical simulations, longitudinal competency tracking, faculty development and institutionalization of artificial intelligence (AI) literacy, standardized evaluation frameworks and regulatory guidance, and ambient AI in smart educational environments. When integrated thoughtfully, GenAI and LLMs may reduce faculty workload and enrich the learner experience while preserving educators’ authority over competency judgments and the humanistic core of medical education. Realizing this potential will require coordinated investment in faculty’s AI literacy, robust governance, equity-focused deployment, and rigorous validation of AI-enhanced educational tools.
The ethics of using artificial intelligence in medical research
Shinae Yu, Sang-Shin Lee, Hyunyong Hwang
Kosin Med J. 2024;39(4):229-237.   Published online December 6, 2024
DOI: https://doi.org/10.7180/kmj.24.140
  • 65,535 View
  • 1,254 Download
  • 19 Citations
Abstract PDFPubReader   ePub   
The integration of artificial intelligence (AI) technologies into medical research introduces significant ethical challenges that necessitate the strengthening of ethical frameworks. This review highlights the issues of privacy, bias, accountability, informed consent, and regulatory compliance as central concerns. AI systems, particularly in medical research, may compromise patient data privacy, perpetuate biases if they are trained on nondiverse datasets, and obscure accountability owing to their “black box” nature. Furthermore, the complexity of the role of AI may affect patients’ informed consent, as they may not fully grasp the extent of AI involvement in their care. Compliance with regulations such as the Health Insurance Portability and Accountability Act and General Data Protection Regulation is essential, as they address liability in cases of AI errors. This review advocates a balanced approach to AI autonomy in clinical decisions, the rigorous validation of AI systems, ongoing monitoring, and robust data governance. Engaging diverse stakeholders is crucial for aligning AI development with ethical norms and addressing practical clinical needs. Ultimately, the proactive management of AI’s ethical implications is vital to ensure that its integration into healthcare improves patient outcomes without compromising ethical integrity.

Citations

Citations to this article as recorded by  
  • Anemia in young women: determinants and artificial intelligence-based management approaches
    Guttapalam Sireesha, D. Madhavi, A. M. Beulah, M. Niharika, C. Pradeepthi
    Frontiers in Artificial Intelligence.2026;[Epub]     CrossRef
  • SERS Meets Artificial Intelligence: A New Frontier in Cancer Diagnosis and Prognosis
    Noor ul Huda, Rana Zaki Abdul Bari, Muhammad Abdullah Javed, Muhammad Naeem Kiani, Yongdong Jin
    Analytical Chemistry.2026; 98(12): 8757.     CrossRef
  • The onco-bariatric paradigm: a tri-phasic metabolic obesity framework for synergizing glucagon-like peptide-1 receptor agonists and metabolic bariatric surgery
    Dong Jin Park, Yoonhong Kim, Dongjae Jeon, Young Suk Park, Kyung Won Seo, Ki Hyun Kim
    Kosin Medical Journal.2026; 41(1): 3.     CrossRef
  • Beyond the algorithm: embedding ethics for trustworthy AI in radiology and oncology
    Mónica Cano Abadía, Melanie Goisauf
    Frontiers in Digital Health.2026;[Epub]     CrossRef
  • Informed Consent in AI-Augmented Dentistry and Dental Research: A Scoping Review
    Tamara Mihut, Corina Marilena Cristache, Luminita Oancea, Victor Nimigean
    Dentistry Journal.2026; 14(6): 320.     CrossRef
  • Artificial Intelligence in Cervical Cytology: Opportunities and Limitations in Screening, Triage, and Diagnostic Support
    Agata Stanek-Widera, Jędrzej Borowczak, Dominik Skiba, Michel-Edwar Mickael, Marzena Łazarczyk, Mateusz Maniewski, Łukasz Szylberg, Andrey Bychkov, Piotr Religa
    Diagnostics.2026; 16(10): 1541.     CrossRef
  • Applications, Challenges, and Future Directions of Large Language Models in Health Care Communication: Scoping Review
    Jing Chang, Ruotong Peng, Xi Chen, Yishu Zhu, Ruting Miao, Zeng Cao, Hui Feng
    Journal of Medical Internet Research.2026; 28: e84726.     CrossRef
  • A survey on medical multimodal retrieval-augmented generation (RAG)
    Ruipeng Wang, Jian Wang, Yan Huang, Haiyang Guo, Junjie Pang
    High-Confidence Computing.2026; : 100415.     CrossRef
  • A Modular Evaluation of AI-Assisted Clinical Documentation
    Julien Delaunay, Maissaa Sarkis, Jordi Solé-Casals, Jordi Cusido
    Applied Sciences.2026; 16(14): 6961.     CrossRef
  • Integrating Artificial Intelligence in Orthopedic Care: Advancements in Bone Care and Future Directions
    Rahul Kumar, Kyle Sporn, Joshua Ong, Ethan Waisberg, Phani Paladugu, Swapna Vaja, Tamer Hage, Tejas C. Sekhar, Amar S. Vadhera, Alex Ngo, Nasif Zaman, Alireza Tavakkoli, Mouayad Masalkhi
    Bioengineering.2025; 12(5): 513.     CrossRef
  • Current Bioinformatics Tools in Precision Oncology
    Tesfaye Wolde, Vipul Bhardwaj, Vijay Pandey
    MedComm.2025;[Epub]     CrossRef
  • Case Report: Intranasal esketamine combined with a form of generative artificial intelligence in the management of treatment-resistant depression
    Alexandre Fraichot, Sophie Favre, Hélène Richard-Lepouriel
    Frontiers in Psychiatry.2025;[Epub]     CrossRef
  • Future Designs of Clinical Trials in Nephrology: Integrating Methodological Innovation and Computational Power
    Camillo Tancredi Strizzi, Francesco Pesce
    Sensors.2025; 25(16): 4909.     CrossRef
  • The revolutionary impact of artificial intelligence in orthopedics: comprehensive review of current benefits and challenges
    Salar Baghbani, Yoosef Mehrabi, Mohammad Movahedinia, Erfan Babaeinejad, Mohammadamin Joshaghanian, Shayan Amiri, Mostafa Shahrezaee
    Journal of Robotic Surgery.2025;[Epub]     CrossRef
  • Human-in-the-Loop Performance of LLM-Assisted Arterial Blood Gas Interpretation: A Single-Center Retrospective Study
    Sergio Ayala-De la Cruz, Paola Elizabeth Arenas-Hernández, María Fernanda Fernández-Herrera, Rebeca Alejandrina Quiñones-Díaz, Jorge Martín Llaca-Díaz, Erik Alejandro Díaz-Chuc, Diana Guadalupe Robles-Espino, Erik Alejandro San Miguel-Garay
    Journal of Clinical Medicine.2025; 14(18): 6676.     CrossRef
  • Applications, Challenges, and Prospects of Generative Artificial Intelligence Empowering Medical Education: Scoping Review
    Yuhang Lin, Zhiheng Luo, Zicheng Ye, Nuoxi Zhong, Lijian Zhao, Long Zhang, Xiaolan Li, Zetao Chen, Yijia Chen
    JMIR Medical Education.2025; 11: e71125.     CrossRef
  • Ética, empatia e IA: como equilibrar decisões automatizadas e julgamento clínico humanizado
    Iranildo Lopes de Oliveira, Rivana Ferreira de Souza, João Victor de Amorim Batista, Iara Costa Silvano, Ana Caroline Rocha de Melo Leite, Rodolfo de Melo Nunes
    Cuadernos de Educación y Desarrollo.2025; 17(10): e9794.     CrossRef
  • Machine learning in lupus nephritis: bridging prediction models and clinical decision-making towards personalized nephrology
    Diego Fernando Garcia-Bañol, Adrianny Mahelis Arias-Choles, Silvia Aldana-Peréz, Gustavo J. Aroca-Martínez, Carlos Guido Musso, Roberto Navarro-Quiroz, Alex Dominguez-Vargas, Henry J. Gonzalez-Torres
    Frontiers in Medicine.2025;[Epub]     CrossRef
  • Ethical Integration of Artificial Intelligence in Nursing Research: An Evidence-based Practice Project from Saudi Arabia
    Jennifer de Beer, Khulud Bababkr Mohammed, Joynalyn Barrios, Salma Elnajjar, Meead Fawaz Aldabahy, Vimela Moodley, Asma Almuntashiri, Maab Basha, Ashwag Othman Eissa, Wejdan Omar Barayan, Shonise Young
    Journal of Nursing Science and Professional Practice.2025; 2(4): 183.     CrossRef
Original article
Capsule endoscopy in Kazakhstan: a multicenter clinical experience
Sang Jun Sohn, Kanat Batyrbekov, Ainura Galiakbarova, Laura Yerdaliyeva, Jamilya Kaibullayeva, Jeongwoo Ju, Haejin Lee, Yeoun Joo Lee
Kosin Med J. 2024;39(3):179-185.   Published online July 26, 2024
DOI: https://doi.org/10.7180/kmj.24.116
  • 8,433 View
  • 54 Download
  • 1 Citations
Abstract PDFPubReader   ePub   
Background
By analyzing small bowel capsule endoscopy (SBCE) performed in two large hospitals in Kazakhstan, we aimed to explore the characteristics of patients representative of Central Asia and the technical characteristics of SBCE.
Methods
SBCE cases were retrospectively analyzed. A descriptive analysis was conducted on the patients’ demographic data, diagnosis, and clinical symptoms. The results of SBCE, such as the lesions found, transit time and retention rate in the stomach and small bowel, and bowel visualization quality, were analyzed. Complications related to SBCE were investigated.
Results
SBCE was performed in 123 patients. Abdominal pain (81.3%) and chronic diarrhea (66.7%) were the most common symptoms, followed by weight loss (25.2%) and gastrointestinal bleeding (15.4%). The most common disease was Crohn’s disease (52.0%). Definite lesions, such as ulcers, polyps, and bleeding, were identified in 55.3% of patients. SBCE was successfully completed in all cases except for 11 (9.1%). The average small bowel transit time was 4 hours and 28 minutes. Excellent visualization (>75% of mucosa) was reported in 82.5% of patients. No patients experienced complications.
Conclusions
SBCE performed in Kazakhstan showed a high diagnostic yield with high-quality patient selection and no complications.

Citations

Citations to this article as recorded by  
  • Exploring the impact of capsule endoscopy in Kazakhstan: a significant milestone
    Jong Yoon Lee
    Kosin Medical Journal.2024; 39(3): 151.     CrossRef

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