Kosin Medical Journal

Sung Su Kim

2 Articles

The Change of Thyroid Stimulating Hormone Values of Healthy Subjects According toTemperature and Aging: Sung Su Kim, Dong Hoon Lew, Ja Yoon Choi, Eun Ju Lee, Min Gyo Kim, Kyong Young Kim, Soo Kyoung Kim, Jung Hwa Jung, Jae Hoon Jung, Jong Ryea l Hahm; Kosin Med J. 2014;29(2):125-134. Published online December 18, 2014; DOI: https://doi.org/10.7180/kmj.2014.29.2.125

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Abstract Objective:

We conducted a study to investigate the normal range for TSH and within-individual variations of TSH according to temperat䴸re and aging.

Patients and Methods:

We enrolled patients who underwent periodic medical examinations five times over a six year period (2007.8~2013.6). Anthropometric data and thyroid ultrasonography were evaluated, and serum TSH, T3, and T4 were assayed.

Results:

Subjects were 19-64 years old, 120 were female, and 208 were male. Reference ranges for TSH were 0.53-4.94 mlU/L in the first test, 0.49-5.61 mlU/L in the second test, 0.46-6.06 mlU/L in the third test, 0.48-5.99 mlU/L in the fourth test, and 0.52-6.3 mlU/L in the fifth test. When the TSH level was analyzed according to temperature and sex, mean TSH was higher in months in which the average monthly temperatures were below 10⁰C in Jinju, Gyeongnam and female. The aging and low temperatures are associated with increased serum TSH concentrations in the within-individual.

Conclusions:

This study showed that aging is associated with increased serum TSH concentrations in the within- individual and serum TSH concentrations are different in the within-individual according to the temperature.

Citations

Citations to this article as recorded by

Thyroid Allostasis–Adaptive Responses of Thyrotropic Feedback Control to Conditions of Strain, Stress, and Developmental Programming
Apostolos Chatzitomaris, Rudolf Hoermann, John E. Midgley, Steffen Hering, Aline Urban, Barbara Dietrich, Assjana Abood, Harald H. Klein, Johannes W. Dietrich
Frontiers in Endocrinology.2017;[Epub] CrossRef

A Case with Empty Sella Syndrome Combined with Multiple Anterior Pituitary Hormone Deficiencies Presenting as Hypoglycemic Coma: Soo Kyoung Kim, Sung Su Kim, Bo Ra Kim, Jung Hwa Jung, Jae Hoon Jung, Jong Ryeal Hahm; Kosin Med J. 2014;29(2):151-155. Published online December 18, 2014; DOI: https://doi.org/10.7180/kmj.2014.29.2.151

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Abstract PDF PubReader: Abstract
A 55-year-old male was admitted to emergency department with a hypoglycemic shock of unknown origin. He was presented with tonic seizure activity after admission. Initial diagnostic procedure could exclude diabetes mellitus, drug side effects, and exogenous insulin application. Detailed evaluation of the patient's history revealed that the patient had experienced repeated hypoglycemic episodes for 2 years. He was diagnosed with hypothyroidism six years ago. Initial laboratory investigations revealed hypoglycemia, hyponatremia, and low plasma cortisol level (0.18 pg/dᄂ)· Sellar magnetic resonance imaging showed empty sella. Replacement therapy with hydrocortisone resulted in the improvement of clinical symptoms. Combined pituitary stimulation test with exception of hypoglycemia induced growth hormone and cortisol stimulation test was performed. The response of thyroid stimulating hormone, prolactin, follicle-stimulating hormone, and luteinizing hormone was normal. We report the case of empty sella syndrome associated with hypoglycemic shock due to with multiple anterior pituitary hormone deficiencies.

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