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Kyun Woo Lee 3 Articles
High Proportion of Nervous System Disease among Major Cause of Under-Five Death in Korea; Compared with OECD 14 Nations (2005-2010)
Hyun Seok Seo, Seok Won Choi, Ji Sung Kim, Jae Yong Choi, Cheol Am Kim, Byeong Hee Son, Kyun Woo Lee, Kwang Wook Koh
Kosin Med J. 2014;29(1):37-45.   Published online December 17, 2014
DOI: https://doi.org/10.7180/kmj.2014.29.1.37
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Abstract PDFPubReader   CrossRef-TDMCrossref - TDM
Abstract Objectives

To compare the mortality rate of children under ages five from different countries by their causes and to explore the cause of death that is relatively higher in South Korea and came up with measures for resolution.

Methods

The statistics were based from section ICD(International Classification of Diseases)-10 of WHO(World Health Organization) Mortality Database. Among the OECD(Organization for Economic Cooperation and Development) countries, 15 countries with higher GDP(Gross Domestic Product) than South Korea were studied by the mortality rate from 2005 to 2010 sorted into two groups: 0 year group and 1-4 years group. Then the cause of death investigated in detail.

Results

Among the 15 countries, average mortality of 0 year group in Korea ranked 8th and the average mortality of 1-4 years group ranked 4th out of 15. There were no significance in the mortality of 0 year group caused by any specific disease, but unnatural death was ranked 2nd after the United States. The natural death of 1-4 years group was ranked 6th, and the unnatural death was ranked 2nd after the Unites States. Among the natural deaths of 1-4 years group, the cause of death significantly higher was found to be disease G(nervous system disease). Among the subgroups of disease G, the orders went epilepsy, cerebral palsy, paralysis, and inflammatory disease.

Conclusions

We have identified major causes of death of children under age 5. The highest proportion of cause of death in 1-4 years group was nervous system disease and we have proposed resolution. Henceforth, this data will be used as a foundational data for formulating policies relation to the Mother-Child Health.

The Study in Vitamin D Concentration in the Blood for Infants with High Level of Alkaline Phosphatase
Ji Sung Kim, Jae Yong Choi, Kyun Woo Lee, Ick Jin Song, Cheol Am Kim, Byeong Hee Son, Jung Hyun Lee
Kosin Med J. 2012;27(1):17-24.   Published online June 11, 2012
DOI: https://doi.org/10.7180/kmj.2012.27.1.17
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Abstract PDFPubReader   ePub   CrossRef-TDMCrossref - TDM
Objectives

Nowadays most infants on exclusively breast feeding have vitamin D deficiency due to the increase of breast feeding. However, domestic research lacks appropriate materials. Therefore, we researched practical clinical aspects of vitamin D deficiency related to breast milk feeding for infants who have a high amount of alkaline phosphatase (> 500 IU/L).

Methods

The subjects of the study were 31 infants with high alkaline phosphatase level. We tested with 25-hydroxycholecalciferol (25-OHD3), parathyroid hormone, calcium, ionized calcium, phosphorus in their blood and with a wrist x-ray. Then, we divided them into two groups of breast feeding and formula feeding and compared the results.

Results

Eighteen infants (58%) out of 31 infants that have high alkaline phosphatase were vitamin D insufficiency or deficiency, and 16 (100%) breast feeding infants of them showed vitamin D deficiency or insufficiency. However, only 2 (13%) of 15 formula feeding infants were at insufficiency. There was a correlation between alkaline phosphatase and 25-OHD3 concentration in multiple regression analysis, but no correlation in other variables was found in group of breast milk feeding infants. There was neither correlation between vitamin D concentration and alkaline phosphatase nor other correlated variables in the group of formula milk feeding infants.

Conclusions

In this study, there was a high probability of vitamin D deficiency in the breast feeding infants with a high alkaline phosphatase level. Therefore, it is considered to be worth utilizing alkaline phosphatase as a screening test for vitamin D deficiency or rickets for breast feeding infants.

Citations

Citations to this article as recorded by  
  • The Role of Vitamin D in Menopausal Medicine
    Mijin Kim, Tae-Hee Kim, Hae-Hyeog Lee, Heung Yeol Kim, Min-Jung Oh
    Kosin Medical Journal.2016; 31(2): 97.     CrossRef
  • The Role of Vitamin D in Menopausal Medicine
    Mijin Kim, Tae-Hee Kim, Hae-Hyeog Lee, Heung Yeol Kim, Min-Jung Oh
    Kosin Medical Journal.2016; 31(2): 97.     CrossRef
  • Recent Updates on Vitamin D and Pediatric Gastrointestinal Diseases
    Ji-Hyun Seo, Ju Young Chang, Ji Sook Park, Chan-Hoo Park, Hee-Shang Youn
    Pediatric Gastroenterology, Hepatology & Nutrition.2012; 15(3): 138.     CrossRef
A Influence of Vesicoureteral Reflux on Treatment of Urinary Tract Infection by E. coli below 1 year of age
Hyoung Dae Kim, Sang Yoon Lee, Kyun Woo Lee, Hyun Kee Chung
Kosin Med J. 2006;21(2):126-132.
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KMJ : Kosin Medical Journal