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Jong Soon Choi 11 Articles
Expression of vascular endothelial growth factor is a clinically useful predictor for aggressive basal cell carcinoma
Jong Soon Choi, Dong Chan Lee, Hee Kyung Chang
Kosin Med J. 2018;33(1):75-84.   Published online January 21, 2018
DOI: https://doi.org/10.7180/kmj.2018.33.1.75
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Abstract PDFPubReader   CrossRef-TDMCrossref - TDM
Objectives

Basal cell carcinoma (BCC) tumors are locally invasive but rarely metastatic. However, aggressive metastatic variants are being increasingly reported in elderly people. Here we investigated the clinical utility of vascular endothelial growth factor (VEGF) as a predictive biomarker for aggressive BCC variants.

Methods

Thirty-five pathologically confirmed cases of BCC that underwent surgical removal in the Plastic Surgery Department between January 1, 2011 and December 31, 2012 were studied. VEGF expression was analyzed in formalin-fixed paraffin-embedded tumor tissue by immunohistochemical staining. Positive staining was defined as more than 10% of the tumor cells showing immunoreactivity. The associations of VEGF expression with various clinicopathologic parameters were analyzed.

Results

The face was the most prevalent site (28/35), with 15 cases from the nose, 6 cases from the eyelid, and 5 cases from the cheek. The patients were aged between 41 and 86 years, with a mean age of 69.26 ± 173.903 years. The mean BCC size was 1.34 ± 3.853 cm, with a range of 0.3 cm to 12.0 cm. The mean tumor invasion depth from the basement epidermal membrane was 0.17 ± 0.035 cm, with a range of 0.03 cm to 1.10 cm. A mean of 5.66 ± 20.938 intraoperative frozen section slides were examined. VEGF was not expressed in 14 of the 35 patients (40.0%), whereas 42.9% of the patients had low expression and 17.1% of the patients had high expression. VEGF expression was significantly associated with age (P = 0.022), size (P = 0.030), site (P = 0.013), tumor invasion depth (P = 0.019), and number of intraoperatively frozen sections (P = 0.003).

Conclusions

These results suggest that VEGF expression as assessed by immunohistochemistry can predict aggressive or poor prognosis in BCC.

Two Cases of Increased Parasympathetic Nerve System in Irritable Bowel Syndrome with Diarrhea as a Predominant Symptom
Eui Kyu Kang, Jong Soon Choi
Kosin Med J. 2013;28(1):49-54.   Published online January 19, 2013
DOI: https://doi.org/10.7180/kmj.2013.28.1.49
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Abstract PDFPubReader   ePub   CrossRef-TDMCrossref - TDM

The irritable bowel syndrome(IBS) is a chronic functional gastrointestinal disorder, characterized by abdominal pain, bloating and bowel disturbance. The pathophysiology of IBS is very complicated. Recent studies indicate that the most important mechanisms include visceral hypersensitivity, abnormal gut motility, autonomic nervous system(ANS) dysfunction and disorder of regulation of the brain-gut axis. Patients with IBS frequently present impaired autonomic regulation. Heart rate variability(HRV) is an acknowledged tool for estimating autonomic function. We experienced two cases of increased parasympathetic nervous system by HRV in irritable bowel syndrome with diarrhea as a predominant symptom

Nutritional Treatment: New Strategy for Management of Chronic Pelvic Pain
Jong Soon Choi, Heung Yeol Kim
Kosin Med J. 2013;28(1):7-12.   Published online August 17, 2012
DOI: https://doi.org/10.7180/kmj.2013.28.1.7
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  • 1 Citations
Abstract PDFPubReader   ePub   CrossRef-TDMCrossref - TDM

Chronic pelvic pain is a common condition in women of reproductive age and can be described as chronic nociceptive, inflammatory and neuropathic pain characterized by spontaneous pain or a response to various stimuli. Oxidative stress is a component of the inflammatory reaction associated with pain processes. Iron and NF-κB are well-known inducers of oxidative stress, and reactive oxygen species (ROS) are associated with chronic pelvic pain and play an important role in the regulation of genes expressing immunoregulators, cytokines, and other molecules. Chronic pelvic pain treatment is often unsatisfactory and limited to symptom control. However, dietary treatment with antioxidants can improve the function of the immune system and overcome free radical damage. Therefore, dietary supplementation is suggested as a means to treat some chronic medical conditions that respond poorly to medication. In summary, dietary treatment with antioxidants could be considered for new strategy for treatment of chronic pelvic pain and may be better tolerated by patients than current treatments.

Citations

Citations to this article as recorded by  
  • Medical and social aspects in women of reproductive age with chronic pelvic pain
    S.О. Shurpyak, O.B. Solomko
    Reproductive health of woman.2021; (6): 71.     CrossRef
The Effectiveness of Medical Communication Skill of Medical Students, through an Emphasis on Role Play
Ho Seob Lihm, Heung Yeol Kim, Jong Soon Choi
Kosin Med J. 2012;27(2):151-159.   Published online December 27, 2012
DOI: https://doi.org/10.7180/kmj.2012.27.2.151
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  • 2 Citations
Abstract PDFPubReader   ePub   CrossRef-TDMCrossref - TDM
Objectives

Medical doctors require outstanding communication skills when meeting with their patients. Thus medical student need to education and training about medical communication skill. More attention is being given to the subject but not many studies have been done in the medical education field. As communication skills are provided to students as a subject in medical educational curriculum, the assessment of its effectiveness needs to be undertaken.

Methods

In the year 2010 and 2011, first-year medical students at The Kosin University College of Medicine took 'Communication skills' course in total, 154 first-year medical students survey results was the modified and translated version of 'Beyer-Fetzer's Essential Elements of Communication Skills Assessment Sheet'. The assessment sheets were used as the pre-test and post-test to analyse the differences, which were put through the paired t-test.

Results

All categories of communication skills showed an improvement. For year 2010, a statistically significant difference was shown into the 22 questions, whereas in 2011, improvements were shown in all questions.

Conclusions

From the result, it is clear that in order to create an effective communication skills program, the content should be more structured and focused on the program objectives.

Citations

Citations to this article as recorded by  
  • The Modified Brief-Structured Observation is Helpful to Understand Students’ Clinical Reasoning Process
    황영은, 서지현, 우향옥, Hee-Shang Youn, HwaokBae, 박정제, 윤인애, 강기련
    Health Communication, the Official Journal of Korean Academy on Communication in Healthcare.2016; 11(1): 1.     CrossRef
  • Curriculum Integration of Communication Simulation to Community Health Nursing Course for Nursing Students: Pilot Study
    Yi-Kyung Ha
    Journal of the Korea Academia-Industrial cooperation Society.2015; 16(4): 2329.     CrossRef
The Effect of Lipoic Acid on Mercury Excretion
Jong Soon Choi
Kosin Med J. 2009;24(1):138-142.   Published online June 30, 2009
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A Case of Hyperprolactinemia with Galactorrhea Induced by Domperidone
Jun Seok Kim, Jong Soon Choi
Kosin Med J. 2009;24(1):197-199.   Published online June 30, 2009
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The Awarness Regarding Hypertension: Comparision of Hypertensive and Non-Hypertensive
Eun Hee Kong, Jong Soon Choi
Kosin Med J. 2008;23(4):137-142.   Published online December 31, 2008
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A Case of Rhabdomyolysis after Doxylamine Overdose
Ho Seob Lihm, Jong Soon Choi
Kosin Med J. 2008;23(4):288-290.   Published online December 31, 2008
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The Expression of Survivin mRNA in Patients with Colorectal Carcinomas to The Liver Metastasis
Jong Soon Choi, Hee Kyung Chang
Kosin Med J. 2008;23(1):26-30.   Published online March 31, 2008
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Health Literacy Regarding Educational Materials on Hypertension
Eun Hee Kong, Jong Soon Choi
Kosin Med J. 2007;22(1):81-88.   Published online June 30, 2007
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Awareness Regarding Hypertension on Hypertensive Patients in a Clinic of Internal Medicine
Eun Hee Kong, Jong Soon Choi
Kosin Med J. 2006;21(1):188-193.
  • 86 View
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KMJ : Kosin Medical Journal