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Jin Hyuk Cho 1 Article
A Case of Glomerulonephritis Associated with Klinefelter' Syndrome
Jin Hyuk Cho, Yeoung Sin Sin, Eun Hee Sim, Min Gyu Park, Dong Heo, Hak Rim
Kosin Med J. 2012;27(2):177-180.   Published online December 27, 2012
DOI: https://doi.org/10.7180/kmj.2012.27.2.177
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Abstract PDFPubReader   ePub   CrossRef-TDMCrossref - TDM

Klinefelter' syndrome is a disorder of sexual differentiation in males, characterized by the presence of two or more X-chromosomes, hypogonadism, and lack of secondary sexual characteristics. The association between Klinefelter' syndrome and glomerulonephritis has been reported, while cases of glomerulonephritis associated with Klinefelter' syndrome are rare. We report the Korean case: a 31-year-old man with Klinefelter' syndrome who developed glomerulonephritis. The patient's urine analysis shows microscopic hematuria and the result of kidney biopsy was minimal change disease. The onset and course of his disease might have been influenced by the sex hormone imbalance.


KMJ : Kosin Medical Journal