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Doo Sik Kim 11 Articles
Hemodynamic Effects of Co-administration of Midazolam during Anesthesia Induction with Propofol and Remifentanil in Hypertensive Patients
Ju Deok Kim, Joo Won Kim, His Chiang Kung, Jun Hong Kang, Hye Young Shin, Doo Sik Kim, Sie Jeong Ryu, Kyung Han Kim
Kosin Med J. 2017;32(1):36-46.   Published online June 30, 2017
DOI: https://doi.org/10.7180/kmj.2017.32.1.36
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Abstract PDFPubReader   ePub   CrossRef-TDMCrossref - TDM
Objectives

Propofol, midazolam and remifentanil are commonly used for clinical anesthesia. We compared the effects of midazolam-propofol-remifentanil and propofol-remifentanil on hemodynamic responses during anesthesia induction in hypertensive patients.

Methods

Seventy-six hypertensive patients with ASA II-III were assigned to receive midazolam-propofol (group MP; n = 38) or propofol (group P; n = 38). Anesthesia was induced with midazolam 0.03 mg/kg (group MP) or saline 0.03 ml/kg (group P). After two minutes, propofol 1.0 mg/kg (group MP) or 1.5 mg/kg (group P) i.v. bolus was administered. Simultaneously, 4 ng/ml of remifentanil target controlled infusion (TCI) was administered in both groups. Anesthesia was maintained using sevoflurane and 2 ng/ml of remifentanil TCI. Systolic, diastolic, and mean blood pressure (SBP, DBP, and MBP) and heart rate (HR) were measured before induction, 2 min after midazolam or normal saline, 2 min after propofol, 1 min after rocuronium, and immediately, 1 min, 2 min, and 3 min after intubation.

Results

SBP, DBP, and MBP decreased after propofol administration and increased immediately after intubation in both groups (P < 0.05). After intubation, SBP, DBP, and MBP decreased more than baseline values in either group. Although the overall BP of Group P was lower than that of Group MP, there were no significant differences except for SBP at 2min after intubation (P < 0.05). HR was no significant difference in either group.

Conclusion

Our results suggest that midazolam-propofol-remifentanil has similar hemodynamic effect with propofol-remifentanil during anesthesia induction in hypertensive patients.

A Comparison of the Recovery Characteristics between Propofol-remifentil and Sevoflurane-remifentail Anesthesia for Total Thyroidectomy
Dong Hee Kang, Jeong Gil Lee, Hyeong Ju Jung, Ju Deok Kim, Soo Bong Yu, Si Jeong Ryu, Gyeong Han Kim, Doo Sik Kim
Kosin Med J. 2013;28(2):137-143.   Published online January 19, 2013
DOI: https://doi.org/10.7180/kmj.2013.28.2.137
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Abstract PDFPubReader   ePub   CrossRef-TDMCrossref - TDM
Objectives

This study was investigated the recovery characteristics of propofol-remifentanil and sevoflurane-remifentanil anesthesia for total thyroidectomy

Methods

Eighty patients in ASA physical status 1 and 2 scheduled for total thyroidectomy were allocated randomly to either group P (n = 40) or group S (n = 40). Anesthesia was maintained with remifentanil effect site concentration (Ce) 1-3 ng/mL and propofol Ce 2-4 μ g/mL in the group P, and was maintained with remifentanil Ce 1-3 ng/mL and sevoflurane 1.5-2% in the group S. Blood pressure, heart rate, and bispectral (BIS) index were measured during perioperative period. The times from discontinuance of anesthetic agent to eye opening, to extubation, and to stating name were measured. Postoperative complications were evaluated.

Objectives

This study was investigated the recovery characteristics of propofol-remifentanil and sevoflurane-remifentanil anesthesia for total thyroidectomy

Methods

Eighty patients in ASA physical status 1 and 2 scheduled for total thyroidectomy were allocated randomly to either group P (n = 40) or group S (n = 40). Anesthesia was maintained with remifentanil effect site concentration (Ce) 1-3 ng/mL and propofol Ce 2-4 μ g/mL in the group P, and was maintained with remifentanil Ce 1-3 ng/mL and sevoflurane 1.5-2% in the group S. Blood pressure, heart rate, and bispectral (BIS) index were measured during perioperative period. The times from discontinuance of anesthetic agent to eye opening, to extubation, and to stating name were measured. Postoperative complications were evaluated.

Results

There were no significant differences between group P and S on the blood pressure, heart rate, and recovery time. BIS index of group P showed lower than that of group S during operation (P < 0.05). The incidences of side effects were similar in the two groups, though the incidence of nausea was higher in the group S (P < 0.05).

Conclusions

Propofol-remifentanil anesthesia was more advantageous than sevoflurane-remifentanil anesthesia for thyroidectomy in view of side effect incidences.

Citations

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  • Comparison of Postoperative Pain and Nausea and Vomiting between Desflurane and Desflurane-remifentanil Anesthesia for Gynecologic Laparoscopic Surgery
    In-Suk Lee, Yun-Mi Kim
    Korean Journal of Women Health Nursing.2015; 21(1): 1.     CrossRef
Analysis of Spontaneous Intracranial Hypotension Treated with Epidural Blood Patch
Doo Sik Kim, Soo Bong Yu, Sang Ho Yoon
Kosin Med J. 2009;24(2):52-56.   Published online December 31, 2009
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Temperature Change During Hepatic Cryotherapy
Doo Sik Kim, Soo Bong Yu
Kosin Med J. 2008;23(4):38-41.   Published online December 31, 2008
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The Analgesic effect of Morphine Sulfate and Ketorolac Administered in Intravenous Patient Controlled Analgesia after Subtotal Gastrectomy
Soo Bong Yu, Kwang Yoon, Doo Sik Kim
Kosin Med J. 2008;23(4):42-46.   Published online December 31, 2008
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The Effect of Memantine in Reducing Tactile Allodynia in Rats with Spinal Nerve Ligation
Doo Sik Kim
Kosin Med J. 2008;23(4):114-118.   Published online December 31, 2008
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Anesthetic Experience of One-Lung Ventilation in Children using Fogarty Catheter as Bronchial Blocker
Soo Bong Yoo, Hyo Seok Kang, Ji Hoon Lim, Doo Sik Kim, Sie Jeong Ryu
Kosin Med J. 2008;23(3):114-117.   Published online September 30, 2008
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Severe Hypoxemia following Methylmethacrylate Bone Cement during Total Elbow Replacement
Tae Ho Chang, Doo Sik Kim, Sie Jeong Ryu, Kyung Han Kim, Se Hwan Kim
Kosin Med J. 2006;21(2):170-174.
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Clinical Usefulness of Propofol-Fentanyl Intravenous Anesthesia
Min Seong Sim, Doo Sik Kim, Sie Jeong Ryu, Kyung Han Kim, Se Hwan Kim, Tae Ho Chang
Kosin Med J. 2006;21(1):120-125.
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Influence of Patient-Controlled Analgesia with Morphine and Fentanyl on the Recoverery of Atracurium Block
Se Hwan Kim, Jung Ho Kim, Doo Sik Kim, Sie Jeong Ryu, Tae Ho Chang, Kyung Han Kim, Ok Sik Han
Kosin Med J. 2006;21(1):172-177.
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Preoperative Dextromethorphan Reduces Postoperative Pain After FESS
Doo Sik Kim, Su Gon Kim
Kosin Med J. 2004;19(1):232-236.
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KMJ : Kosin Medical Journal